New study: Massive Aluminum levels in Autism brains, is this the smoking gun for vaccines?

“These are some of the highest values for aluminium in human brain tissue yet recorded.” — Professor Chris Exley of Keele University, discussing new findings of Aluminum levels in the brains of people with autism

BY J.B. HANDLEY November 27, 2017

STAFFORDSHIRE, England — Professor Chris Exley is a formidable scientist, which is perhaps more important than you think, because a study he published today with his colleagues in the Journal of Trace Elements in Medicine and Biology may just be the “smoking gun” to prove that vaccines are triggering autism that we’ve all been waiting for. Professor Exley is a Professor of Bioinorganic Chemistry at Keele University in Staffordshire, England. He received a Ph.D. in a subject that makes him highly qualified to author this latest paper: “the ecotoxicology of aluminium.”

READ MORE: https://medium.com/@jbhandley/new-study-massive-aluminum-levels-in-autism-brains-is-this-the-smoking-gun-for-vaccines-54ae85ec2a9c

 

http://www.sciencedirect.com/science/article/pii/S0946672X17308763

Journal of Trace Elements in Medicine and Biology
Available online 26 November 2017

In Press, Accepted Manuscript — Note to users



Aluminium in brain tissue in autism

• Matthew Molda,
• Dorcas Umarb,
• Andrew Kingc,
• Christopher Exleya,

https://doi.org/10.1016/j.jtemb.2017.11.012
Get rights and content
Under a Creative Commons license


Open Access
Abstract
Autism spectrum disorder is a neurodevelopmental disorder of unknown aetiology. It is suggested to involve both genetic susceptibility and environmental factors including in the latter environmental toxins. Human exposure to the environmental toxin aluminium has been linked, if tentatively, to autism spectrum disorder. Herein we have used transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy. The aluminium content of brain tissue in autism was consistently high. The mean (standard deviation) aluminium content across all 5 individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. These are some of the highest values for aluminium in human brain tissue yet recorded and one has to question why, for example, the aluminium content of the occipital lobe of a 15 year old boy would be 8.74 (11.59) μg/g dry wt.? Aluminium-selective fluorescence microscopy was used to identify aluminium in brain tissue in 10 donors. While aluminium was imaged associated with neurones it appeared to be present intracellularly in microglia-like cells and other inflammatory non-neuronal cells in the meninges, vasculature, grey and white matter. The pre-eminence of intracellular aluminium associated with non-neuronal cells was a standout observation in autism brain tissue and may offer clues as to both the origin of the brain aluminium as well as a putative role in autism spectrum disorder.

Keywords

• Human exposure to aluminium;
• human brain tissue;
• autism spectrum disorder;
• transversely heated atomic absorption spectrometry;
• aluminium-selective fluorescence microscopy